I am using libvirt 3.6 version on Ubuntu 17.10 and create domain with command: virt-install --name dc02 --memory 1024,maxmemory=2048 --vcpus 1 --cpu host --boot uefi,hd,network --disk /var/lib/libvirt/images/dc02.qcow2,bus=virtio --network bridge=br.27,model=virtio --video=qxl --memballoon virtio --hvm --controller usb3 --machine=q35 --graphics spice,listen=192.168.69.108 Domain boot failed with BSOD message "Unaccesible boot device", but when i change virtio-drive to sata-drive, its successfuly boot ps -ef output for virtio-drive look like: libvirt+ 39726 1 45 19:59 ? 00:00:06 qemu-system-x86_64 -enable-kvm -name guest=dc02,debug-threads=on -S -object secret,id=masterKey0,format=raw,file=/var/lib/libvirt/qemu/domain-11-dc02/master-key.aes -machine pc-q35-2.10,accel=kvm,usb=off,vmport=off,dump-guest-core=off -cpu SandyBridge,vme=on,ss=on,vmx=on,pcid=on,hypervisor=on,arat=on,tsc_adjust=on,xsaveopt=on,pdpe1gb=on -drive file=/usr/share/OVMF/OVMF_CODE.fd,if=pflash,format=raw,unit=0,readonly=on -drive file=/var/lib/libvirt/qemu/nvram/dc02_VARS.fd,if=pflash,format=raw,unit=1 -m 2048 -realtime mlock=off -smp 1,sockets=1,cores=1,threads=1 -uuid fab3a566-46ad-4b2c-9e65-26cb685af33a -no-user-config -nodefaults -chardev socket,id=charmonitor,path=/var/lib/libvirt/qemu/domain-11-dc02/monitor.sock,server,nowait -mon chardev=charmonitor,id=monitor,mode=control -rtc base=utc,driftfix=slew -global kvm-pit.lost_tick_policy=delay -no-hpet -no-shutdown -global ICH9-LPC.disable_s3=1 -global ICH9-LPC.disable_s4=1 -boot strict=on -device pcie-root-port,port=0x10,chassis=1,id=pci.1,bus=pcie.0,multifunction=on,addr=0x2 -device i82801b11-bridge,id=pci.2,bus=pcie.0,addr=0x1e -device pci-bridge,chassis_nr=3,id=pci.3,bus=pci.2,addr=0x0 -device pcie-root-port,port=0x11,chassis=4,id=pci.4,bus=pcie.0,addr=0x2.0x1 -device pcie-root-port,port=0x12,chassis=5,id=pci.5,bus=pcie.0,addr=0x2.0x2 -device pcie-root-port,port=0x13,chassis=6,id=pci.6,bus=pcie.0,addr=0x2.0x3 -device pcie-root-port,port=0x14,chassis=7,id=pci.7,bus=pcie.0,addr=0x2.0x4 -device pcie-root-port,port=0x15,chassis=8,id=pci.8,bus=pcie.0,addr=0x2.0x5 -device nec-usb-xhci,id=usb,bus=pci.4,addr=0x0 -device virtio-serial-pci,id=virtio-serial0,bus=pci.5,addr=0x0 -drive file=/var/lib/libvirt/images/dc02.qcow2,format=qcow2,if=none,id=drive-virtio-disk0 -device virtio-blk-pci,scsi=off,bus=pci.6,addr=0x0,drive=drive-virtio-disk0,id=virtio-disk0,bootindex=1 -netdev tap,fd=27,id=hostnet0,vhost=on,vhostfd=29 -device virtio-net-pci,netdev=hostnet0,id=net0,mac=52:54:00:16:88:b3,bus=pci.1,addr=0x0,bootindex=2 -chardev pty,id=charserial0 -device isa-serial,chardev=charserial0,id=serial0 -chardev spicevmc,id=charchannel0,name=vdagent -device virtserialport,bus=virtio-serial0.0,nr=1,chardev=charchannel0,id=channel0,name=com.redhat.spice.0 -spice port=5900,addr=192.168.69.108,disable-ticketing,image-compression=off,seamless-migration=on -device qxl-vga,id=video0,ram_size=67108864,vram_size=67108864,vram64_size_mb=0,vgamem_mb=16,max_outputs=1,bus=pcie.0,addr=0x1 -device intel-hda,id=sound0,bus=pci.3,addr=0x1 -device hda-duplex,id=sound0-codec0,bus=sound0.0,cad=0 -chardev spicevmc,id=charredir0,name=usbredir -device usb-redir,chardev=charredir0,id=redir0,bus=usb.0,port=1 -chardev spicevmc,id=charredir1,name=usbredir -device usb-redir,chardev=charredir1,id=redir1,bus=usb.0,port=2 -device virtio-balloon-pci,id=balloon0,bus=pci.7,addr=0x0 -msg timestamp=on But when i run this domain with qemu-system its succsessfuly boot and work. Cmd looks like: qemu-system-x86_64 -machine type=pc-q35-2.8 -accel kvm -cpu host \ -cdrom /var/lib/libvirt/images/virtio-win-0.1.141.iso \ --bios /usr/share/OVMF/OVMF_CODE.fd \ -m 2048 -smp 2 -drive file=/var/lib/libvirt/images/dc02.qcow2,index=0,media=disk,if=virtio -boot menu=on \ -spice addr=192.168.69.108,port=5910,disable-ticketing I cannot fugire out where i went wrong